Endocrine Abstracts

Purpose: Neuroendocrine dysfunction represents a frequent consequence of traumatic brain injury (TBI) but has not been studied longitudinally as yet. Here we attempt to identify predictors of late endocrine insufficiency following TBI.Methods: 71 consecutive patients (age 18 – 87 yrs) with TBI assessed by an intial CT and the Glasgow Coma Score (GCS) were prospectively studied as to their pituitary function on day 0, 3 and 7 and dynamically 24–...

Introduction: Cytokines are produced in different tissues under physiological and pathophysiological conditions. The present study was performed to compare local concentrations of cytokines in subcutaneous adipose tissue and muscle using the open flow microperfusion (OFM) technique, as well as to investigate systemic effects of insulin on interstitial concentrations of these mediators.Methods: Ten healthy volunteers (age: 27±4 years, BMI: 22.6±...